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Items for the Week:
Issue 152 Item 14 Anemia Common Among
Diabetics on Wednesday, May 28 @ 00:00:00
EDT
Anemia is common in patients with diabetes,
especially in those with albuminuria or reduced
renal function, (23%) had unrecognized anemia.
" Anemia is common in diabetes,
potentially contributing to the pathogenesis of
diabetes complications," Dr. Merlin C. Thomas, of
Baker Medical Research Institute, Melbourne,
Australia, and colleagues note. In a
cross-sectional study of 820 diabetic patients,
they examined the prevalence and independent
predictors of anemia.
Over a 2-year
period, the researchers obtained a full blood
count and routine blood and urine tests. They used
multiple and logistic regression analyses to
determine predictors of the most recent Hb
concentration and anemia.
The
investigators report that 190 patients (23%) had
unrecognized anemia. "This prevalence is two to
three times higher than for patients with
comparable renal impairment and iron stores in the
general population," Dr. Thomas and colleagues
explain.
Transferrin saturation,
glomerular filtration rate, sex, albumin excretion
rate, and HbA1c level independently predicted Hb
levels (all p < 0.0001). Compared with
normoalbuminuric patients with preserved renal
function, those with microalbuminuria and those
with macroalbuminuria were more likely to have
anemia (odds ratio 2.3 and 10.1, respectively).
" This study demonstrates that anemia is
an early and common complication of diabetes," the
researchers conclude. In their study population,
strong predictors of anemia included a glomerular
filtration rate of less than 60 mL/min and
macroalbuminuria. Diabetes Care 2003;26:1164-1169.
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FOOD FACT: In 1961 Bread, Chips or other
pre meal foods were charged for or only given free
13% of the time. In 2003 Bread, Chips or other pre
meal foods are given free 66% of the time.
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